《Stand By Me Doraemon 2》Nobita - following his previous adventure - has managed to change his future for the better, making Shizuka marry him. Taken by despair and triggered by past memories when he found a hand sewn teddy bear made for him by his beloved grandmother, he then decides to return to the past to re-meet her.

She had died when he was very young. Nobita`s grandmother is happy that Nobita has gone back in time to be with her, and confides in him a great desire of hers - that she wants to meet his future bride.

Meanwhile, the Nobita of the future who is about to get married with Shizuka and crown his `dream of happiness`, is seized by a panic attack and flees into the past to see Doraemon again, fearing that he is not the right person for Shizuka.